One thing I'm known for by friends of mine is that I don't always look to conventional instruments to make music.
While I'm a "classically trained" (?) trombone player, I enjoy making music out of things that you may not have seen or may feel is a bit weird.
It baffles some people how I play tunes using my old iPhone, something which I've uploaded to YouTube:
http://www.youtube.com/watch?v=vj3uE4Glegs
Another instrument that you may not have heard of is the theremin. I bought one of these because I was fascinated at how other people play them and wanted to try it for myself. A theremin is probably the only instrument out there that is played without touching it. It uses magnetic disturbance (capacitance) to produce the sound.
I've recently discovered that my Etherwave Standard is double non-linear, meaning that the distance between each note varies and the distance between the octaves also vary - meaning more chance for wrong notes! :P
Here's my attempt at playing My Destiny from Sonic the Hedgehog (2006):